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Medicinal chemistry of Fentanyl Citrate

Introduction :   Fentanyl Citrate belongs to the group of Anesthetics particularly General Anesthetics as Basal Anesthetics.. Description...

Introduction: 
Fentanyl Citrate belongs to the group of Anesthetics particularly General Anesthetics as Basal Anesthetics..

Description

It is employed basically as an analgesic for the control of pain associated with all kinds of surgery. It may also be used an an adjunct to all drugs commonly employed for regional and general anaesthesia. It is one of the components in ‘Fentanyl citrate and Droperidol Injection’ which is used as premedication for anaesthesia and also as an supplement for induction and maintenance of anaesthesia

Analysis


N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide 2-hydroxypropane-1,2,3-tricarboxylate
Chemical Formula: C28H36N2O8
Exact Mass: 528.25
Molecular Weight: 528.59
m/z: 528.25 (100.0%), 529.25 (31.0%), 530.25 (6.4%)
Elemental Analysis: C, 63.62; H, 6.86; N, 5.30; O, 24.21


Structure and Synthesis of Fentanyl Citrate

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